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COVID-19 (coronavirus)

COVID-19 (coronavirus)

Who hasn’t heard of COVID-19? It’s an infectious disease caused by a virus called Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV2) which emerged in December 2019.[1] In just a few months, it has turned the world as we know it upside down. You may be facing local restrictions, worrying about getting sick, or scared of infecting your loved ones. With everything going on, the situation can feel very daunting and out of your control.

Fortunately, thanks to record-speed scientific advances, there is hope for the future. And while COVID-19 is still at large, the best way to protect yourself is to be aware of the disease, how it spreads, and the things you can do to try and prevent it.[2]

ما المقصود بمرض كوفيد-19؟

يرمز كوفيد-19 إلى مرض فيروس كورونا 2019‏.[3] وهو مرضٌ يسببه أحد أنواع فيروس كورونا، وهي مجموعة من الفيروسات التي تنتشر بين الحيوانات ويمكن أن تصيب البشر.[1]

يمكن أن تسبب فيروسات كورونا أيضًا أمراضًا خطيرة أخرى، مثل المتلازمة التنفسية الحادة والشديدة (سارس) والمتلازمة التنفسية الشرق أوسطية (ميرس)، وكذلك نزلات البرد.[3]

إنَّ فيروس كورونا الذي يسبب مرض كوفيد-19، سارس كوف 2، هو أحد فيروسات كورونا تم اكتشافه لأول مرة في البشر في ووهان، الصين، عام 2019‏.[1]

ينتشر مرض كوفيد-19 في الغالب من خلال الرذاذ المحمول عبر الهواء عندما يَسعل أحد الأشخاص المصابين أو يعطس أو يتحدث أو يتنفس على مسافة قريبة (مترين) من الآخرين، [4] حيث يدخل الفيروس جسمك عندما تتنفس أو إذا قمت بلمس عينيك أو أنفك أو فمك بيدك الملوثة بقطرات الرذاذ التي تحمل الفيروس.[1]

عندما يُصاب شخصٌ ما بفيروس لأول مرة، يبدأ عمل الجهاز المناعي ويُطلق استجابةً لمحاربة العدوى، [5] حيث يعمل على تنشيط العديد من الخلايا التي تشمل خلايا الدم البيضاء البائية والتائية التي تُطلق بعد ذلك جزئيات تُعرف باسم السيتوكينات التي تساعد على محاربة العدوى.[5][6][7] لكن، عند الإصابة بفيروس كوفيد-19، يمكن أن يتداخل الفيروس مع الاستجابة المناعية الطبيعية لدى بعض الأشخاص ويتسبب في فرط نشاطها.[7] ويمكنها تنشيط سيتوكينات أكثر من اللازم، ما يتسبب فيما يُعرف باسم عاصفة السيتوكين.[8] ويؤدي هذا الأمر إلى خلل في مسارات الاستجابة الطبيعية، ما قد يشكِّل تهديدًا للحياة.[8]

يعاني معظم الأشخاص المصابين بمرض كوفيد-19 من مرض تنفسي خفيف إلى متوسط وسيتمكنون من التماثل للشفاء من تلقاء أنفسهم.[2] ومع ذلك، قد يكون كبار السن وأولئك الذين يعانون من مشكلات طبية أساسية أكثر عرضة للإصابة بمرض خطير.[2]لهذا السبب من المهم جدًا منع انتشاره في مجتمعاتنا.



What are the symptoms of COVID-19?

COVID-19 affects different people in different ways.9 Most people will have a mild to moderate illness that appears within two weeks of infection, and they recover without needing any special treatment.10

If you have mild symptoms, you should look after yourself at home, but if it becomes serious you will need to seek immediate medical attention.9 Always call before visiting your doctor or health facility.

Common symptoms9

Less common symptoms9

Serious symptoms9

Common symptoms9

  • Fever
  • Dry cough
  • Tiredness

Less common symptoms9

  • Aches and pains
  • Sore throat
  • Diarrhoea
  • Conjunctivitis
  • Headache
  • Loss of taste or smell
  • Rash on skin, or discolouration of fingers or toes

Serious symptoms9

  • Difficulty breathing or shortness of breath
  • Chest pain or pressure
  • Loss of speech or movement

Some people may continue to experience symptoms even after they have initially recovered (often called ‘long COVID-19’) or even long-term organ damage.11 While many people do recover quickly, it is another reason to be cautious.11

How common is COVID-19?

We’re sure you’re aware of just how common COVID-19 is right now. The situation is changing all the time and will depend on where you live, but in most areas the virus is still around at very high levels.12 And while it’s still around, we all need to take precautions.

Anyone can catch COVID-19, but certain people are more likely to have a serious disease.10 This includes everyone over the age of 60,13 and those with health conditions like hypertension, chronic respiratory disease, and cardiovascular disease.10 Certain medications might put you at higher risk, too.14 Speak to your doctor if you think you might be more at risk.

Prevention

It is important to prevent infection and slow the spread of COVID-19, to help protect yourself and those around you.15 Follow local guidelines and take necessary precautions and minimise travel and gathering in large crowds. Rules can feel annoying, upsetting, or frustrating, but they are there to help you.

Vaccination

Thanks to the amazing efforts of researchers and international health bodies, there are now several approved vaccines available with more in development.16 This means many countries are now offering vaccinations against COVID-19.

Vaccines have been a game-changer against other infectious diseases in the past, allowing us to prevent and control 25 once uncontrollable infections.17 Vaccines are the safest possible way to protect against diseases such as COVID-19.17 Those who are hospitalised with the severe disease might receive supportive treatment like oxygen therapy to help them breathe.18

Caring for someone with COVID-19

Caring for someone with COVID-19 comes with an extra challenge – you can’t get too close! It can feel really difficult, both practically and mentally, to keep your distance from a loved one (especially if they feel unwell), but it will help protect you and others from infection.19

  • If they live with you, they should use a separate bedroom and bathroom if possible and keep a window open to air out any shared space19
  • Make sure they drink plenty of fluids and rest well19
  • Medicines may help with a fever19
  • Help them get groceries, prescriptions or anything else they need19
  • Keep an eye out for signs they are getting worse, and call your doctor or emergency services if they are showing symptoms of severe disease19

If you have been in close contact with them, you will also need to stay at home yourself in case you have been infected too.19

Questions to ask your doctor

The list below includes example questions to help start a conversation with your health care provider. There may be other relevant questions based on your symptoms, stage, and medical history that are not listed here.

  • Is there any reason I might be more at risk of serious disease?
  • Does my work or lifestyle put me more at risk of infection, and what can I do to help prevent it?

Janssen & COVID-19

Janssen is committed to identifying and providing solutions during times of crisis, such as COVID-19. With vaccines now available, we hope that our efforts will help protect people around the world and, eventually, help bring this pandemic to an end.

    Glossary

    • COVID-19:Coronavirus disease, an infectious disease caused by a coronavirus: SARS-CoV-2.[1]
    • MERS: Middle East respiratory syndrome, a viral respiratory disease caused by coronavirus.[3]
    • SARS-CoV-2: The virus that causes COVID-19.[1]
    • SARS: Severe acute respiratory syndrome, a viral respiratory disease caused by coronavirus.[3]

    المراجع

    Memorial Sloan Kettering Cancer Center. Multiple Myeloma Symptoms. https://www.mskcc.org/cancer-care/types/multiple-myeloma/multiple-myeloma-symptoms. Last accessed April 2021.
    American Cancer Society. Non-medical treatments for pain. https://www. cancer.org/treatment/treatments-and-side-effects/physical-side-effects/pain/ non-medical-treatments-for-cancer-pain.html. Last accessed Oct 2018.
    Yong K, et al. Br J Haematol. 2016;175:252–264.
    Snowden JA, et al. Br J Haematol. 2011;154:76–103.
    Drugs.com. Multiple Myeloma. Available at: https://www.drugs.com/cg/multiple-myeloma.html. Last accessed April 2021.
    Myeloma UK. Fatigue infoguide. Available at: www.myeloma.org.uk/wp-content/ uploads/2018/03/Myeloma-UK-Fatigue-Infoguide.pdf. Last accessed Aug 2018.
    Multiple Myeloma Research Foundation website. Symptoms, side effects and complications. http://www.myeloma.org/sites/default/files/images/publications/UnderstandingPDF/concisereview.pdf. Last accessed April 2021.
    Myeloma UK. Myeloma and the kidney infoguide. Available at: www.myeloma. org.uk/wp-content/uploads/2018/03/Myeloma-UK-Kidney-Infoguide.pdf. Last accessed Aug 2018.